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Achieva 3.0T for advanced neuroradiology at Yeditepe University

Best Practice
Kovanlikaya, Ilhami Istanbul, Yeditepe University Hospital Turkey

Achieva 3.0T for advanced neuroradiology at Yeditepe University Hospital

Just over a year since Yeditepe University Hospital (Istanbul) became operational, the multi-specialty medical center has built a reputation as a world-class facility. A centerpiece at Yeditepe is its thriving neurological science institute. Yeditepe acquired the Achieva 3.0T system - only the second whole-body 3.0T in Turkey - to provide the imaging power needed to fully characterize brain tumors pre-surgically. Using diffusion tensor imaging, perfusion-weighted imaging, spectroscopy, BOLD fMRI and conventional imaging techniques, Yeditepe radiologists provide neurosurgeons with the imaging data they need to avoid eloquent cortex.


 Prof. Ilhami Kovanlikaya, M.D. Yeditepe University Hospital.
Prof. Ilhami Kovanlikaya, M.D.
Yeditepe University Hospital.

Employing multiple techniques to make interventions more precise

By virtue of advanced imaging techniques, such as MR spectroscopy, BOLD fMRI, diffusion tensor imaging and perfusion-weighted imaging, most brain tumors leave very little to hide in terms of composition, vascularity, dimensions and proximity to sensitive cortical tissues. And these methods are even more powerful when paired with the 3.0T field strength, which affords maximum signal to resolve even subtle anatomical details.


Yeditepe neuroradiologists and neuroscience physicians appreciated this fact, and - realizing that neuro cases would represent about 60 percent of the hospital's MRI volume - lobbied the center's funding body, the non-profit Iztek Foundation to invest in a 3.0T scanner. Ultimately, the foundation chose to partner with Philips in equipping the entire facility with not just an MRI system, but also top-of-the-line multi-detector CT, PET-CT, flat panel digital subtraction angio, nuclear medicine systems and ultrasound units.


"The Achieva 3.0T with Quasar Dual gradients and Ambient Experience was chosen because we thought Achieva had the most sophisticated neuro package, including multi-nuclear spectroscopy," says Professor Ilhami Kovanlikaya, M.D., chief of the department of radiology. "Philips also offered automatic software updates and committed to a multi-year technical support contract."

Optimal tumor characterization

Every brain tumor patient referred to Yeditepe's department of radiology receives an advanced brain scan, which includes MR spectroscopy, BOLD fMRI, DTI, perfusion-weighted imaging and conventional sequences.


"MR spectroscopy gives us information regarding the lesion's metabolic composition - whether we're dealing with an aggressive malignant neoplasm or a benign mass, while perfusion-weighted imaging can help us determine the blood supply of the mass," Prof. Kovanlikaya observes. "Furthermore, BOLD fMRI is an extremely valuable technique to assist in understanding the mass's relationship with the motor strip or language areas - which are critical to avoid during surgery."


Diffusion tensor imaging (DTI) helps Yeditepe radiologists appreciate the relationship between the tumor and white matter fiber tracts - the brain's communication superhighway, which also must be avoided during surgery.


"For DTI and tractography, the PRIDE workstation has been very useful," he says. "I input all the raw DTI data from the scanner and the PRIDE software automatically calculates and outputs fractional anisotropy maps and tractography for whatever fiber region I select. It's an excellent program for determining the course of white matter fibers."


Yeditepe radiologists also use their battery of neuro techniques in assessing the post-surgical and/or post-radiation treatment follow-up of patients, Prof. Kovanlikaya says. "We can instantly determine the patient's response to treatment regimes, and also it is much easier to differentiate, for example, possible radiation necrosis from recurrent tumor using these advanced neuroimaging techniques."



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Nov 22, 2006

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Best Practice
Achieva 3.0T
Release 1, Release 2
Quasar Dual
Brain, Neuro

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