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Lymphoma treatment response

Case Study
Vandecaveye, Vincent, M.D., Ph.D. Leuven, University of Leuven

Patient history

A patient with lymphoma underwent CT, PET and 3.0T whole body MR, exams before and 2 weeks after start of therapy at University Hospital Leuven, Belgium.

MR examination

The MR examination on the Achieva 3.0T TX with MultiTransmit comprises a fast whole-body anatomical scan (which serves for DWIBS planning) and a single free-breathing whole-body DWI scan at b-values of 0 and 1000, optimized for visualizing lymph node, liver and skeletal/soft-tissue lesions. The exam takes only 20 minutes. The Integrated Body coil was used.

Images


The CT-scan two weeks after start of chemotherapy shows no different volume of the mass. FDG-PET shows a significant decrease of FDG-uptake, while WB-DWI shows significant decrease of b1000 signal intensity, correlating to a significant increase in ADC.

Diagnosis

Both PET and WB MRI findings indicated good tumor response. Two year follow-up in the patient revealed no tumor recurrence.

Clinical impact of using WB DWI:

DWIBS on Achieva 3.0T TX clearly visualized good tumor response after start of chemotherapy, while CT did not. The MR result is confirmed by the PET result.

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Sep 8, 2010

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Case Study
Achieva 3.0T
Release 2, Release 3
DWIBS, Hip, iliac wing, lymphoma, Musculoskeletal, Oncology, Pelvis, PET, Total Body, whole body DWI
 

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