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MR spectroscopy of a 35-year-old woman with breast cancer

Case Study
Van Cauter, Sofie, M.D. University Hospitals Leuven • Belgium

Patient history

35-year-old woman with history of breast cancer experiencing difficulties in balance and motoric coordination.

MR examination

Achieva 3.0T TX was used for the examination.

MR images



Post contrast T1-weighted MRI shows an enhancing lesion in the right cerebellar hemisphere. Because of her history, differential diagnosis is needed between metastasis and primary tumor. Spectroscopy in the lesion shows extremely low to undetectable NAA, elevated choline and a pronounced lipid peak. The virtually absent NAA makes it more likely that the lesions are metastases. This was confirmed on histopathology.

Diagnosis

Breast metastasis.

Impact of 3.0T MR spectroscopy

Applying SENSE in two directions has enabled the Leuven team to dramatically shorten the scan time of MR spectroscopic imaging (MRSI) in the brain to about three and a half minutes without loss of spectral or spatial resolution, while maintaining sufficient SNR. These shorter scan times make it practical to include MR spectroscopy in routine brain MR exams.


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Jul 31, 2012

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Case Study
Achieva 3.0T TX
Breast, Neuro, Oncology, Spectroscopy
 

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