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MRI of child with neurofibromatosis type 1

Case Study
Arrigoni, Filippo, M.D. E. Medea Research Institute • Italy

Patient history

The patient is a 5.5-year-old female with neurofibromatosis type 1 and a small corpus callosum.

MR examination

The examination was performed using the Achieva 3.0T with 32-channel SENSE Head coil.


Voxels 0.43 x 0.43 x 3 mm, TR 4100, TE 82

T1-3D TFE, voxels 1 x 1 x 1 mm, 8 min.

Voxels 0.3 x 0.3 x 1.1 mm TR 5600, TE 15
Voxels 0.3 x 0.3 x 1.1 mm, TR 5600, TE 15

DTI tractography

MR results

Multiple hyperintense rounded lesions (white arrows) are evident in the basal ganglia and thalami in the coronal images. Axial images with very high resolution provide a better definition of these lesions. The patient also has a small corpus callosum (sagittal image) with hyperintense lesions in the right Probst bundle (black arrows). DTI tractography shows a small but apparently complete corpus callosum.

Clinical impact of using Achieva 3.0T with 32-channel SENSE Head coil

This configuration allowed us to develop sequences focussing on very high resolution. We need to go into the finer detail of the pediatric brain anatomy and structure. DTI can often depict white matter abnormalities.

Related reading

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Oct 30, 2012

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Case Study
Achieva 3.0T
Release 3
32ch SENSE Head coil, Brain, DTI, Neuro, neurofibromatosis, Pediatric

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