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Whole body MRI of skeletal and splenic manifestation of non Hodgkin lymphoma

Case Study
Schmidt, Gerwin, M.D. Radiology Munich Center • Germany
Rother, Tobias, M.D. Radiology Munich Center • Germany

Skeletal and splenic manifestation of non Hodgkin lymphoma

Patient history

A 33-year-old male with history of non-Hodgkin lymphoma underwent an MRI exam on Ingenia 1.5T at Radiology Practice Munich Center in order to visualize clinically suspected recurrent disease.

MR examination

The examination was performed on Ingenia 1.5T using the dS Torso coil solution.

Whole-body MRI was performed using T1W TSE and STIR imaging (4 stations, matrix 400x400, 6 mm slices). In addition, whole-body diffusion imaging was done (3 stations, matrix 192x192, 6 mm slices) with MIP. The total examination time is within 40 minutes.


Whole-body MRI with MIP unmasks a focal area of diffusion restriction in the left scapular region.

Subsequent contrast-enhanced 3D mDIXON imaging reveals a bone manifestation of a lesion in the left scapular angle.

Furthermore, multifocal splenic infiltration is depicted. Note that the splenic lesions are veiled by the high physiological background diffusion signal in splenic tissue.


The findings are compatible with skeletal and splenic tumor recurrence of non-Hodgkin lymphoma. Further total body follow-up imaging according to therapeutic regime is advised.

Impact of using Ingenia 1.5T whole body imaging

Whole-body MRI allows rapid visualization of lesions in this lymphoma patient. A finding of multifocal organ manifestations has a decisive impact on further patient management and therapeutic regime.

The fully digital Ingenia 1.5T MR system allows rapid whole body MRI with homogeneous, high image quality in depicting these lesions. Additionally, state-of-the-art techniques such as whole body DWI can be included in the exam protocol, which further enhances the capability for visualizing lesions in oncology patients.

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May 20, 2014

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Case Study
Ingenia 1.5T
Release 4
Body, dS Torso coil solution, dStream, DWI, DWIBS, mDIXON, Oncology, Spleen, Whole body

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