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256-slice CTA evaluation of CABG

Publication
Philips CT Clinical Science Philips Healthcare • USA

Effect of heart rate, heart rate variability and z-axis location on image quality

Gramer BM, Martinez PD, Chin AS, Sylvestre MP, Larrive S, Stevens LM, Noiseux N, Soulez G, Rummeny EJ, Chartrand-Lefebvre C.

* This article was originally published in the March 2014 issue of PLOS ONE.
Purpose 
The objective of this study is to assess the effect of heart rate, heart rate variability and z-axis location on coronary artery bypass graft (CABG) image quality using a 256-slice computed tomography (CT) scanner.

Methods 
A total of 78 patients with 254 CABG (762 graft segments) were recruited to undergo CABG assessment with 256- slice CT and prospective ECG-gating. Two observers rated graft segments for image quality on a 5-point scale. Quantitative measurements were also made. Logistic and cumulative link mixed models were used to assess the predictors of graft image quality.

Results 
Graft image quality was judged as diagnostic (scores 5 (excellent), 4 (good) and 3 (moderate)) in 96.6% of the 762 segments. Interobserver agreement was excellent (kappa $0.90). Graft image quality was not affected by heart rate level. However, high heart rate variability was associated with an important and significant image quality deterioration (odds ratio 4.31; p = 0.036). Distal graft segments had significantly lower image quality scores than proximal segments (p = 0.02). Significantly higher noise was noted at the origin of the mammary grafts (p = 0.001), owing to streak artifacts from the shoulders.

Conclusion 
CABG imaging with 270-msec rotation 256-slice CT and prospective ECG-gating showed an adequate image quality in 96.6% of graft segments, and an excellent interobserver agreement. Graft image quality was not influenced by heart rate level. Image quality scores were however significantly decreased in patients with high heart rate variability, as well as in distal graft segments, which are closer to the heart.
For more information about this publication, check out the PubMed listing for this article.


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Publication
iCT, IntelliSpace Portal
bypass grafts, CABG, Cardiac, coronary angiography, ECG-gated, image quality, prospective, quantitative, Shoulder, Vascular
 

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