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Hypertropic cardiomyopathy

Case Study
Flamm, Scott, M.D. Cleveland Clinic USA

Hypertrophic cardiomyopathy

Patient history

A 37-year-old male with syncope and shortness of breath, with no family history of sudden cardiac death, presented for an MR examination at the Cleveland Clinic, Ohio, USA.

MR examination

MRI was performed using an Achieva 1.5T XR scanner with the SENSE XL Torso coil.


Single-shot SSFP and half Fourier acquired single-shot turbo spin echo (ssTSE) images were acquired to delineate the anatomy.


Cine SSFP images were then acquired in multiple orientations to characterize myocardial motion and thickness.


In-plane velocity encoded phase contrast imaging in the three-chamber (LVOT) orientation was used to visualize and quantify the jet in the LV outflow tract.


All images were acquired with retrospective VCG gating during short (typically 8-14 second) breath holds, except the ssTSE images which were acquired with respiratory triggering during free breathing.



ExamCard used:



The short axis views show moderate to severe asymetrical hypertrophy of the interventricular septum (red arrows).



The three-chamber view (LVOT) shows a high velocity jet in the LV outflow tract (red arrow heads). Phase contrast sequence is used for quantifying the velocity of this jet (3.4 m/sec).




Hypertrophic obstructive cardiomyopathy.

Clinical impact of Achieva 1.5T XR

Even when the Achieva XR is running at 1.5T, it has the gradient capabilities of a 3.0T scanner. This allows shorter TRs and TEs and, as a result, in the same breath hold, accomplishes imaging that has higher spatial resolution, higher temporal resolution, or both. Another advantage of the Achieva 1.5T XR are the shorter scan times, reducing examination times. 


The additional flow quantification images, using the Achieva 1.5T XR, are acquired with good reproducibilty, within a single breath hold, and with retrospective gating to cover the entire cardiac cycle.


The integration of ExamCards with the Extended Workspace (EWS) is particularly advantageous. With the customizable display protocols and the tight integration with the EWS display protocols, series of long and short axis images can be displayed on a single screen and all be synchronized.



Related information:

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Apr 30, 2010

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Case Study
Achieva 1.5T XR
Release 2.6
Quasar Dual
Cardiac, Cardiac Morphology, Function Cine, Function Non-Cine, heart

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