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MR spectroscopy of a patient with Multiple Sclerosis

Case Study
Van Cauter, Sofie, M.D. University Hospitals Leuven • Belgium

Patient history

In a patient with known Multiple Sclerosis, MR was performed to investigate if there was evidence for disease activity and consequently therapeutic strategies should be changed.

MR examination

Achieva 3.0T TX is used for the examination.

Images



Several lesions are seen on the FLAIR images. Note that some lesions are contrast-enhancing, suggesting active lesions. The spectra of an active lesion show elevated choline, myoinositol and lactate, decreased NAA. All of these component changes are indicative of active lesions.

Diagnosis

Active Multiple Sclerosis. After this exam the patient was treated with corticosteroids to suppress the inflammation.

Clinical impact of 3.0T MR Spectroscopy

Applying SENSE in two directions has enabled the Leuven team to dramatically shorten the scan time of MR spectroscopic imaging (MRSI) in the brain to about three and a half minutes without loss of spectral or spatial resolution, while maintaining sufficient SNR. These shorter scan times make it practical to include MR spectroscopy in routine brain MR exams.


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Case Study
Achieva 3.0T TX
multiple sclerosis, Spectroscopy
 

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