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Multi-parametric prostate MRI exam

Case Study
Punwani, Shonit, M.D., Ph.D. UCL • United Kingdom

Multiparametric prostate MRI exam

Patient history

A patient with an initial diagnosis of prostate cancer presented at University College London Hospitals for an MRI examination of the prostate on Achieva 3.0T TX in order localize the lesion.

MR examination

A multi-parametric MRI exam was performed with Achieva 3.0T TX using a 32-channel SENSE Cardiac coil.

MR images

Click on an image to enlarge
 Axial ADC map Axial T2W Axial b2000 diffusion weighted imaging
Axial ADC map
Axial T2W
Axial b2000 diffusion weighted imaging
The axial ADC map demonstrates reduced diffusion within the anterior left transition zone of the prostate. This is consistent with increased cellularity within a tumor. Note that this region would not be undersampled by a standard TRUS biopsy procedure, and without MRI assisting in targeting a diagnosis of localized tumor could not be confirmed.

The axial T2-weighted images demonstrates a subtle more homogenous area of reduced T2 signal within the anterior left transition zone similar in appearance to adenoma. The axial b2000 diffusion weighted image demonstrates significant residual signal within the left anterior transition zone at the tumor site. Signal elsewhere is almost completely absent.

Diagnosis

MRI demonstrates a lesion in the the anterior left transition zone of the prostate.

Clinical impact of multiparametric prostate imaging

Multi-parametric MRI was able to clearly loalize the lesion while a standard TRUS procedure would undersample this region.

Being able to localize lesions also opens the possibility to provide focal therapies, which treat only a part of the prostate rather than removing the entire organ.

Related reading:



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Jun 11, 2014

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Case Study
Achieva 3.0T TX
ADC, b2000, Body, DWI, multi-parametric, Oncology, Prostate, SENSE Cardiac coil
 

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