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Recurrent cutaneous melanoma

Case Study
Vandecaveye, Vincent, M.D., Ph.D. Leuven, University of Leuven
Dr. Pans, Steven, M.D. Leuven, University of Leuven

Patient history

A patient with recurrent cutaneous melanoma underwent FDG-PET, CT and whole body diffusion-weighted MRI on the Achieva 3.0T TX at University Hospital Leuven, Belgium.

MR examination

The MR examination on the Achieva 3.0T TX with MultiTransmit comprises a fast whole-body anatomical scan (which serves for DWIBS planning) and a single free-breathing whole-body DWI scan at b-values of 0 and 1000, optimized for visualizing lymph node, liver and skeletal/soft-tissue lesions. The exam takes only 20 minutes. The Integrated Body coil was used.

Images


FDG-PET shows a hypermetabolic focus in the right axilla, compatible with a metastatic adenopathy (arrowhead), as well as a subcutaneous metastasis in the right gluteal area (arrow). Co-registered CT in the lung window shows the presence of multiple lung metastases (circles). WB-DWI clearly shows the metastatic mass in the right axilla as a b1000 hyperintense area (arrowhead), corresponding to an ADC of 0.00073 mm2/s, two subcutaneous metastases as b1000 hyperintense nodules in the right gluteal muscle (arrows) and multiple lung metastases, also depicted as b1000 hyperintense lesions (circles).

Diagnosis

The findings are consistent with recurrent cutaneous melanoma.

Clinical impact of using WB DWI:

Thanks to its exceptional contrast-to-noise ratio and the resulting improved lesion conspicuity, diffusion-weighted MR imaging (DWI) offers additional value to conventional MRI for lesion visualization. The benefits of the technique are even more apparent at 3.0T, which enables even higher contrast-to-noise ratios.

Related reading:



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Sep 8, 2010

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Case Study
Achieva 3.0T
Release 2, Release 3
axilla, Body, CT, DWIBS, Hip, Lungs, melanoma, Musculoskeletal, Oncology, PET, Total Body, whole body DWI
 

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