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Using MRI with pCASL for brain perfusion imaging

Case Study
Reginster, Pierre, M.D. CHC Saint Joseph Hospital • Belgium
Martin, Bénédicte, M.D. CHC Saint Joseph Hospital • Belgium

Pseudo-Continuous Arterial Spin Labeling (pCASL) is an arterial spin labeling technique showing high SNR and good sensitivity to whole brain perfusion. The pCASL technique combines advantages from continuous ASL and pulsed ASL, such as high SNR and high labeling efficiency.
 
CHC Saint Joseph Hospital (Liege, Belgium) is using pCASL for high performance brain perfusion imaging without contrast.

pCASL of right frontal glioblastoma

As pCASL does not need any contrast agent, it may be a patient-friendly and economic alternative for dynamic susceptibility contrast imaging. Whole brain pCASL was acquired using Achieva 3.0T TX, 16-channel NeuroVascular coil, 13 slices, voxels 2.73 x 2.73 x 7 mm, scan time 4:08 min. The overlay is created on IntelliSpace Portal.

 Post contrast 3D T1W FFE T2* DSC perfusion
Post contrast 3D T1W FFE
T2* DSC perfusion
 pCASL pCASL overlay on anatomic image
pCASL
pCASL overlay on anatomic image
 
 

pCASL of left frontal metastasis

Whole brain pCASL was acquired using Achieva 3.0T TX.
The overlay is created on IntelliSpace Portal.

 Post contrast 3D T1W FFE T2* DSC perfusion eADC
Post contrast 3D T1W FFE
T2* DSC perfusion
eADC
 pCASL pCASL overlay on T1W
pCASL
pCASL overlay on T1W


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Case Study
Achieva 3.0T TX, Ingenia 3.0T
16-channel NV coil, Brain, Brain Perfusion, Glioblastoma, IntelliSpace, metastasis, Neuro, pCASL, Perfusion, T2*
 

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