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Comparison of MDCT vs. echocardiography for assessing regional left ventricular function

Publication
CT Marketing Philips Healthcare

Lessick J, Mutlak D, Rispler S, Ghersin E, Dragu R, Litmanovich D, Engel A, Reisner S and Agmon Y.

* Originally published in the October 2005 issue of the American Journal of Cardiology.

 

Multidetector computed tomography (MDCT) of the heart is a rapidly developing technique mainly used to evaluate the coronary arteries. However, it is also capable of evaluating ventricular function. It compares well with magnetic resonance imaging in calculating volumes and ejection fractions, but little has been reported on its ability to assess left ventricular (LV) segmental wall motion (LVSWM). This study compared semi-quantitative LVSWM scoring by MDCT with echocardiography as the gold standard. Thirty-nine patients underwent MDCT angiography on a 16-slice scanner. Short- and long-axis LV slices were created at different phases of the cardiac cycle and visually evaluated using cine mode. Echocardiography was performed <48 hours after MDCT for 21 patients after acute myocardial infarctions and <1 month after MDCT for 18 patients without acute myocardial infarctions. Two blinded observers scored the MDCT and echocardiographic examinations according to the 16-segment model, scoring each segment from 1 (normal) to 3 (akinetic). Segmental dysfunction was found in 27 patients by echocardiography and in 24 by MDCT. An identical score was given by the two methods in 502 of 616 assessable segments (82%). Using a binary analysis (normal or abnormal), there was 89% agreement (546 of 616 segments). MDCT had a sensitivity of 66% (103 of 155 segments) and a specificity of 96% (443 of 461 segments) compared with echocardiography as the gold standard. Most disagreements occurred in the right coronary artery segments. In conclusion, MDCT can be used to evaluate LVSWM, showing good agreement with echocardiography, except for the right coronary artery segments.

For more information about this publication, check out the PubMed listing for this article.


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Publication
Brilliance 16 Power, Brilliance 16-slice
Cardiac, cine, coronary angiography, coronary arteries, left ventricle, LV/RV Function, myocardial viability, RCA, Vascular
 

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