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1.5T ExamCard gray matter heterotopia - Utrecht

de Kok, Wendy Philips Healthcare
de Kort, Gerard Utrecht, University Medical Center

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MR images

Sagittal T1W_SE Full brain coverage.DUAL_SE Proton density and T2-weighting in the axial plane.
Coronal T2W_FLAIR TR, TI and TE optimized for good T2-weighting in the brain.
Sagittal T1W_SE
Coronal T2W_FLAIR
Full brain coverage.
Proton density and T2-weighting in the axial plane.
TR, TI and TE optimized for good T2-weighting in the brain.
T1W_3D_TFE Axial reconstruction. Isotropic voxels.Diffusion tensor imaging Trace images of 15 diffusion direction.T1W_3D_FFE Post-contrast acquisition.
Diffusion tensor imaging
Axial reconstruction. Isotropic voxels.
Trace images of 15 diffusion direction.
Post-contrast acquisition.


A comprehensive brain examination is performed in a pediatric patient that presented with seizures. The 8-channel SENSE Head coil is used. Sequences in three orthogonal directions and with various contrast weightings are acquired.


A T1-weighted SE sequence is acquired in the axial plane. Full brain coverage is provided in short scan time. The images generate a quick anatomical overview of the entire brain.


Secondly, a DUAL_SE is performed. Echo times are optimized in relation to the patient's age and generate good proton-density and T2-weighted contrast.


Then, a coronal T2W_FLAIR is acquired. Repetition time and inversion delay time are chosen such that CSF is nicely suppressed. Additionally, inversion delay time and echo time are long to optimize T2-weighted contrast in gray and white matter, again in relation to the age of the child.


The next scan is a T1-weighted 3D TFE scan with full brain coverage and isotropic voxels of 1x1x1 mm. Reconstuctions with equal spatial resolution can be made in any plane. TSE factor and shot length are chosen such that the prepulse delay time is about 950 ms. This results in optimal T1-weighted contrast between gray and white matter.


A single shot diffusion tensor sequence with b=800, also with full brain coverage and isotropic voxels (2x2x2mm) is added. Fifteen diffusion directions are measured, FA maps can be generated. SENSE is used in this scan, to reduce the echo train length. Susceptibility related distortions and blurring effects are reduced.


Finally, a T1-weighted 3D_FFE sequence is acquired after administration of contrast agent. Possible laesion enhancement can be visualized.


Scan time of the latter three sequences is relatively long, however, this should not pose a problem as the child is sedated. Total scan time is approximately 40 minutes.

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Jul 5, 2005

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Achieva 1.5T
Release 1
Brain, Neuro, Pediatric

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